Arimixyl is a remedy for blocking conversion of steroids into estrogen. It is also used against gynecomastia when Nolvaxyl no longer works. Many steroids, especially the strong mass builders, convert into estrogen by the aromatase enzyme. Certainly at the end of a cycle this can ruin the results. Arimixyl binds to aromatase so that it can no longer convert steroids. In addition, it ensures that the body’s own hormone production starts up faster. Arimixyl can be taken alongside a cycle with testosterone, for example, to prevent estrogen-related side effects such as water retention and fat. This, however, also ensures that the gained muscle mass is preserved.
Active period for Arimixyl (Anastrazole): 2 Days
Administration: Pills, By Mouth
Dose: 0.5 to 1 mg/day
Water etention: No, it ensures a drier look
High blood pressure: No
Liver damage: No or very light
Aromatization: No, that’s the right thing
DHT conversion: No
Blocks hormone production: No, stimulates hormone production correctly.
Arimixyl, Letroxyl and Aromaxyl are third generation aromatase inhibitors, previous generations also switched off enzymes that were responsible for other (useful) conversions of hormones. This third generation focuses specifically on the aromatase enzyme. They are used in the treatment of certain cancers when treatment with Nolvaxyl has failed. Where Nolvaxyl blocks the estrogen receptors, these aromatase inhibitors work one step earlier, because they prevent estrogen from being formed. The aromatase enzyme converts certain hormones (testosterone, methandienone, nandrolone) into estrogen. When the dose of these hormones is high, a lot of estrogen is produced, which on the one hand leads to a larger increase in mass and on the other hand can cause unpleasant side effects like gynecomastia. Arimixyl, Letroxyl and Aromaxyl bind to the aromatase enzyme so that it can no longer ensure the conversion to estrogen. Letroxyl is the strongest aromatase inhibitor of the 3, it eliminates 99% of the aromatase present, for Arimixyl and Aromaxyl it is “only” 97 and 95%. In most bodybuilding related sources it is claimed that the above percentages indicate the reduction of estrogen, that is NOT true, those numbers are in a range of 80 to 98% with most values around 85%. How much the formation of estrogen is suppressed also depends on the type of estrogen. The ratios between the different agents are the same here as in the inhibition of aromatase discussed above.
All three aromatase inhibitors are claimed to stimulate the production of testosterone and Aromaxyl also increases the amount of IGF (Insulin-like Growth Factor). A disadvantage of these products is that they are bad for the level of cholesterol in the blood, due to the excess suppression of estrogen formation. A source claims that Letroxyl is able to make gynecomastia present, besides an experience with the product this is substantiated with scientific research. 2.5 mg of Letroxyl were taken per day and slowly reduced. In combination with testosterone, Proviroxyl is still the best choice because of the synergy that these two products have with each other.
The aromatase inhibitors are normally used throughout the cycle to suppress the formation of estrogen. This may be necessary in cycles with steroids that can aromatize: testosterone, dianoxyl, nandroxyl or large amounts of boldaxyl. They can also be used during the follow-up of a severe cycle and / or for a competition to obtain the dry bodybuilder look. When gynecomastia occurs during a course of treatment, this can be remedied immediately with nolvaxyl or clomixyl and an aromatase inhibitor can be taken immediately to reduce the amount of estrogen so that the problems do not come back immediately. Nolvaxyl and clomixyl block only the estrogen receptor, the amount of estrogen remains high so that the problems with stopping nolvaxyl or clomixyl can come back immediately. From letroxyl 0.25 to 0.5 mg per day should be taken, the dose for arimixyl is 0.5 to 1 mg per day and for aromaxyl it is 5 to 25 mg per day. The pills can be taken every day or every other day.
Adverse reactions that are experienced with arimixyl, letroxyl and aromaxyl are mainly due to the low amount of estrogen in the body as a result of the use of these agents. When the aromatase inhibitors are used for bodybuilding, the period of intake will not be long. As a result, most side effects that occur in cancer patients will not apply to bodybuilders. The drugs are bad for the amount of cholesterol in the blood, with aromaxyl this side effect seems less or not to occur. At a high dose, the libido of the user can temporarily be low or completely absent. Furthermore, hot flushes can occur, fatigue, headaches, dizziness, bowel problems and pain in bones and muscles.